INGESTIGATION OF SIDE EFFECTS AFTER RENAL GENE THERAPY (RNAi) AND LUPUS NEPHRITIS IVIG THERAPY ON MOUSE MODELS PhD thesis

نویسندگان

  • Dr Zsuzsanna Rácz
  • Péter Hamar
  • Zsombor Lacza
چکیده

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Transcriptional activation of HIF-1 by a ROS-ERK axis underlies the resistance to photodynamic therapy

Photodynamic therapy (PDT), a promising treatment option for cancer, involves the activation of a photosensitizer (PS) by local irradiation with visible light. Excitation of the PS leads to a series of photochemical reactions and consequently the local generation of harmful reactive oxygen species (ROS) causing limited or none systemic defects. However, the development of resistance to this pro...

متن کامل

Dual role of IFT57 in cilia and nucleus in Paramecium

Ackonwledgements This work presented here was down at the Centre de Génétique Moléculair, CNRS under the supervision of Dr.Jean COHEN. Foremost, I would like to express my deepest appreciation to my advisor Dr. Jean COHEN for the continuous support for my thesis throughout my studies in France. In particular, I am grateful to Madam France KOLL for her comments on the thesis and precious suggest...

متن کامل

Supramolecular self-assembled nanoparticles mediate oral delivery of therapeutic TNF-α siRNA against systemic inflammation.

Intervention of the inflammation cascade with tumor necrosis factor-a (TNF-a) monoclonal antibodies or receptors represents a major approach in clinical immunotherapy against inflammatory diseases, which however, often suffers from high cost, autoimmunity to antibodies, and various side effects. siRNA-mediated RNA interference (RNAi) has recently emerged as a potent modality in regulating gene ...

متن کامل

Epstein-Barr Virus EBER Transcripts Affect miRNA-Mediated Regulation of Specific Targets and Are Processed to

The oncogenic Epstein-Barr virus (EBV) expresses 44 mature microRNAs and two non-coding EBER RNAs of 167 (EBER1) and 172 (EBER2) nt length. MiRNA profiling of NK/T cell lines and primary cells and Northern blotting of EBV-infected cell lines and primary tumors revealed processing of EBER1 to short 5′-derived RNAs of approximately 23, 52 and 70 nt (EBER123, EBER152, and EBER170) and of EBER2 to ...

متن کامل

Rudra Interrupts Receptor Signaling Complexes to Negatively Regulate the IMD Pathway

Insects rely primarily on innate immune responses to fight pathogens. In Drosophila, antimicrobial peptides are key contributors to host defense. Antimicrobial peptide gene expression is regulated by the IMD and Toll pathways. Bacterial peptidoglycans trigger these pathways, through recognition by peptidoglycan recognition proteins (PGRPs). DAP-type peptidoglycan triggers the IMD pathway via PG...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2012